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Fig. 1 | BMC Rheumatology

Fig. 1

From: BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study

Fig. 1

RA Aetiopathogenesis. Environmental factors act upon genetic predisposition to cause breach of tolerance (transition A); Unknown factors act on an individual with pre-RA to trigger active RA (transition B); Treatment induces remission (transition C); Unknown factors trigger flare (transition D). Colours denote what is well investigated (green), the focus of the study (orange) and additional processes that this study could inform (pink)

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BMC Rheumatology

ISSN: 2520-1026

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