Table 1 Patient demographics and clinical characteristics reported by physicians
Total (N = 730) | Low disease activity (N = 46) | Higher active disease (N = 684) | p-value | |
|---|---|---|---|---|
Age, years | ||||
n | 730 | 46 | 684 | 0.3068 |
Mean (SD) | 39.9 (12.6) | 38.1 (13.5) | 40.0 (12.5) | |
Range | 17–80 | 20–74 | 17–80 | |
Sex, n (%) | ||||
n | 730 | 46 | 684 | 1.0000 |
Female | 646 (88.5) | 41 (89.1) | 605 (88.5) | |
Male | 84 (11.5) | 5 (10.9) | 79 (11.5) | |
Ethnicity, n (%) | ||||
n | 730 | 46 | 684 | 0.4179 |
White | 496 (67.9) | 34 (73.9) | 462 (67.5) | |
Non-White | 234 (32.1) | 12 (26.1) | 222 (32.5) | |
Time since diagnosis, years | ||||
n | 719 | 44 | 675 | 0.5169 |
Mean (SD) | 5.0 (5.6) | 5.5 (5.8) | 4.9 (5.6) | |
Range | 0.0–31.0 | 0.5–30.9 | 0.0–31.0 | |
Current disease severity, n (%) | ||||
n | 725 | 45 | 680 | 0.0291 |
Mild | 427 (58.9) | 35 (77.8) | 392 (57.6) | |
Moderate | 265 (36.6) | 9 (20.0) | 256 (37.6) | |
Severe | 33 (4.6) | 1 (2.2) | 32 (4.7) | |
Current treatment, n (%) | ||||
n | 730 | 46 | 684 | |
Steroid | 690 (94.5) | 17 (37.0) | 673 (98.4) | < 0.0001 |
Immunosuppressant | 413 (56.6) | 20 (43.5) | 393 (57.5) | 0.0671 |
Anti-malarial | 482 (66.0) | 32 (69.6) | 450 (65.8) | 0.7480 |
Biologic | 30 (4.1) | 3 (6.5) | 27 (3.9) | 0.4277 |
Patients receiving belimumab | 10 (1.4) | 1 (2.2) | 9 (1.3) | 0.4806 |
Other | 140 (19.2) | 12 (26.1) | 128 (18.7) | 0.2444 |
Treatment ever received | ||||
n | 730 | 46 | 684 | 684 |
Steroid | 713 (97.7) | 33 (71.7) | 680 (99.4) | < 0.0001 |
Immunosuppressant | 477 (65.3) | 27 (58.7) | 450 (65.8) | 0.3397 |
Anti-malarial | 566 (77.5) | 37 (80.4) | 529 (77.3) | 0.7177 |
Biologic | 58 (7.9) | 5 (10.9) | 53 (7.7) | 0.4009 |
Other | 202 (27.7) | 14 (30.4) | 188 (27.5) | 0.7335 |
Current treatment line | ||||
n | 730 | 46 | 684 | 0.4917 |
1 | 223 (30.5) | 11 (23.9) | 212 (31.0) | |
2 | 285 (39.0) | 21 (45.7) | 264 (38.6) | |
3 | 129 (17.7) | 7 (15.2) | 122 (17.8) | |
4 5 | 58 (7.9) 25 (3.4) | 4 (8.7) 3 (6.5) | 54 (7.9) 22 (3.2) | |
6 | 10 (1.4) | 0 (0.0) | 10 (1.5) |