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Table 2 Time to first organ damage for newly diagnosed SLE cohort without pre-index organ damage versus comparator cohorta

From: Clinical and economic burden of organ damage among patients with systemic lupus erythematosus in a real-world setting in Germany

Organ domain

Parameter estimate

Standard error

p value

Hazard ratio

(95% confidence interval)

Any organ damage

0.47348

0.03874

< 0.0001

2.578 (2.215–3.001)

Ocular

0.38422

0.06288

< 0.0001

2.156 (1.685–2.759)

Neuropsychiatric

0.42128

0.07576

< 0.0001

2.322 (1.726–3.125)

Renal

0.75135

0.13060

< 0.0001

4.494 (2.693–7.498)

Pulmonary

1.09683

0.20112

< 0.0001

8.968 (4.077–19.728)

Cardiovascular

0.56146

0.09545

< 0.0001

3.074 (2.114–4.469)

Peripheral vascular

0.65125

0.13699

< 0.0001

3.678 (2.150–6.293)

Gastrointestinal

0.27635

0.13122

0.0352

1.738 (1.039–2.907)

Musculoskeletal

0.69552

0.19325

0.0003

4.019 (1.884–8.572)

Cutaneous

1.71621

0.18933

< 0.0001

30.951 (14.736–65.012)

Gonadal

0.06367

0.14398

0.6584

1.136 (0.646–1.997)

Diabetes

0.10127

0.12263

0.4089

1.225 (0.757–1.980)

Malignancy

0.09435

0.11792

0.4236

1.208 (0.761–1.917)

  1. aResults of an adjusted Cox regression
  2. SLE: systemic lupus erythematosus