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Table 1 Causal efect between SLE and osteoporosis by diferent MR analysis methods

From: Association between systemic lupus erythematosus and osteoporosis: a mendelian randomization analysis

Exposure

Outcome

method

nSNP

OR

95% CI

SE

p value

SLE

Osteoporosis

Inverse variance weighted

26

1.038

1.007

1.070

0.016

0.017

SLE

Osteoporosis

Weighted median

26

1.028

0.984

1.073

0.022

0.213

SLE

Osteoporosis

MR Egger

26

1.028

0.942

1.122

0.044

0.541

  1. SLE, Systemic lupus erythematosus; SNP, Single nucleotide polymorphism; SE, Standard Error; MR, Mendelian randomization