Table 5 Prednisolone treatment in PMR
Treatment duration | Prednisolone dosage (mg) |
|---|---|
First 2–4 weeks | 15 |
Next 2–4 weeks | 12.5 |
Next 4 weeks | 10 |
Next 4 weeks | 8.75 (e.g. 10 and 7.5 alternate days) |
Next 4 weeks | 7.5 |
Next 4 weeks | 6.25 |
Next 4 weeks | 5 |
Next 4 weeks | 3.75 |
Next 4 weeks | 2.5 |
Next 4 weeks | 1.25 |
Discontinuation | 0 |
Relapse | Increase prednisolone to the pre-relapse dose and taper gradually (within 4–8 weeks) to the dose at which the relapse occurred. |
Consider methotrexate | In patients with comorbidities that may be exacerbated by GC therapy and in patients with relapsing disease or GC-related adverse events. |