Fig. 5

Modification of the gut microbiome induced by intermittent fasting in the collagen-induced arthritis model. (A) Composition and structure of the microbial community of feces from control and IF mice. (B) Alpha diversity index (Chao-1); (C) Beta diversity at the OTU level is spatially represented by a non-multidimensional scaling analysis (NMDS) using Bray Curtis dissimilarity distances. (D) Heat map of the abundance of bacterial species in the two study groups. (E) Graphs from the univariate analysis of those classes, orders, and genera different in the group treated with IF (p < 0.01 and FDR < 0.05)