Table 1 Clinical characteristics, demographic information, and laboratory data of patients with rheumatoid arthritis (n = 305)
From: Evaluation of hematological markers as prognostic tools in rheumatoid arthritis
Characteristics | High RA activity (59) | Moderate RA activity (96) | Low RA activity (45) | RA in remission (105) | P Value |
|---|---|---|---|---|---|
Age (Mean ± SD) | 52.1 ± 12.3 | 53.1 ± 12.2 | 53.5 ± 13.2 | 49.2 ± 12.9 | 0.71 |
Sex (Female%) | 91% | 88% | 91% | 88% | 0.72 |
Disease Duration (months) | 43 (1-503) | 57 (2-417) | 48 (1-393) | 68 (1-640) | 0.66 |
Tender joint count, median (range) | 18 (2–30) | 6 (0–22) | 1 (0–9) | 0 (0–2) | 0.000 |
Swollen joint count, median (range) | 17 (3–35) | 6 (0–28) | 1 (0–11) | 0 (0–6) | 0.000 |
ESR (mm/h) | 37.2 ± 3.4 | 30.9, ± 2.3 | 29.9 ± 2.9 | 15.2 ± 0.9 | 0.000 |
CRP value (mg/dL), Mean ± SD | 16.1 ± 2.5 | 13.9 ± 2.2 | 11.4 ± 2.1 | 7.8 ± 1.2 | 0.01 |
Anti CCP positivity (%) | 29 (49%) | 41 (42%) | 22 (49%) | 38 (36%) | 0.32 |
RF positivity (%) | 40 (68%) | 53 (55%) | 28 (62%) | 50 (48%) | 0.07 |
ANA positivity (%) | 22 (37%) | 24 (25%) | 7 (15%) | 27 (25%) | 0.09 |
WBCs (103/mm3) | 7.5 ± 0.4 | 7.7 ± 0.3 | 7.5 ± 0.3 | 8.3 ± 0.7 | 0.62 |
RBC (106/𝜇L) | 4.4 ± 0.1 | 4.6 ± 0.1 | 4.7 ± 0.1 | 4.6 ± 0.1 | 0.06 |
Hemoglobin (g/dL) | 12.4 ± 0.2 | 12.9 ± 0.1 | 13.1 ± 0.2 | 13.3 ± 0.1 | 0.01 |
Hematocrit (%) | 37.6 ± 0.6 | 39.5 ± 0.5 | 40.1 ± 0.7 | 39.7 ± 0.5 | 0.02 |
MCV (FL) | 85.7 ± 1.1 | 84.9 ± 1.2 | 85.1 ± 1.1 | 85.5 ± 0.8 | 0.95 |
MCH (Pg) | 28.4 ± 0.4 | 28.7 ± 0.4 | 28.1 ± 0.6 | 28.6 ± 0.3 | 0.74 |
MCHC (gl/dl) | 32.6 ± 0.3 | 32.6 ± 0.2 | 32.7 ± 0.3 | 32.9 ± 0.2 | 0.64 |
RDW value (%), Mean ± SD | 15.7 ± 0.4 | 15.1 ± 0.3 | 15.1 ± 0.4 | 14.2 ± 0.2 | 0.006 |
MPV value (fL), Mean ± SD | 12.3 ± 1.6 | 10.7 ± 0.2 | 9.6 ± 0.3 | 8.9 ± 0.2 | 0.003 |
Platelet (10³/µL), Mean ± SD | 284 ± 11.2 | 300 ± 9.4 | 299 ± 16.8 | 259 ± 8.4 | 0.009 |
Neutrophils (%), Mean ± SD | 66 ± 1.5 | 62 ± 1.1 | 59 ± 1.5 | 58 ± 1.2 | 0.000 |
Lymphocytes (%), Mean ± SD | 25 ± 1.5 | 26 ± 0.9 | 30 ± 1.5 | 30 ± 1.1 | 0.02 |
Monocyte (%), Mean ± SD | 4 ± 0.4 | 5 ± 0.3 | 4 ± 0.3 | 5 ± 0.2 | 0.06 |
NLR (Mean ± SD) | 3.6 ± 0.3 | 2.8 ± 0.2 | 3.5 ± 1.1 | 2.8 ± 0.4 | 0.52 |
PLR (Mean ± SD) | 14.8 ± 1.3 | 13.5 ± 1.1 | 14.5 ± 3.5 | 12.1 ± 1.6 | 0.68 |
LMR (Mean ± SD) | 9.8 ± 1.4 | 9.2 ± 0.9 | 9.7 ± 1.2 | 11.4 ± 4.1 | 0.93 |