Table 1 Baseline characteristics of participants and study outcomes at baseline stratified by SU Quartiles
Characteristics | Overall | SU Quartiles | P-value | |||
|---|---|---|---|---|---|---|
Quartile 1 [108–400µmol/L] | Quartile 2 [400–493µmol/L] | Quartile 3 [493–580µmol/L] | Quartile 4 [580–1250µmol/L] | |||
Number of participants | 2866 | 717 (25.0) | 717 (25.0) | 716 (25.0) | 716 (25.0) | Â |
Age | Â | Â | Â | Â | Â | Â |
 Median [IQR] | 61 [48, 74] | 65 [53, 76] | 62 [51, 73] | 57 [43, 72] | 60 [45, 73] | < 0.001 |
 Mean (SD) | 60.1 (16.6) | 63.5 (15.2) | 61.0 (14.8) | 57.4 (17.7) | 58.5 (17.9) | < 0.001 |
Sex | Â | Â | Â | Â | Â | Â |
 Male | 2273 (79.3) | 512 (71.4) | 606 (84.5) | 591 (82.5) | 564 (78.8) | < 0.001 |
 Female | 593 (20.7) | 205 (28.6) | 111 (15.5) | 125 (17.5) | 152 (21.2) |  |
Ethnic group | Â | Â | Â | Â | Â | Â |
 Chinese | 2178 (76.0) | 574 (80.1) | 571 (79.6) | 525 (73.3) | 508 (70.9) | < 0.001 |
 Malay | 368 (12.8) | 53 (7.4) | 82 (11.4) | 111 (15.5) | 122 (17.0) |  |
 Indian | 122 (4.3) | 41 (5.7) | 27 (3.8) | 29 (4.1) | 25 (3.5) |  |
 Others | 198 (6.9) | 49 (6.8) | 37 (5.2) | 51 (7.1) | 61 (8.5) |  |
CCI, median (IQR) | 0 [0, 2] | 1 [0, 2] | 0 [0, 2] | 0 [0, 2] | 1 [0, 4] | < 0.001 |
SU level at recruitment (µmol/L) |  |  |  |  |  |  |
 Median [IQR] | 493 [400, 580] | 336 [285, 374] | 451 [427, 473] | 532 [513, 555] | 637 [605, 687] | < 0.001 |
 Range | 108–1250 | 108–400 | 400–493 | 493–580 | 580–1250 |  |
SU Category* |  |  |  |  |  | < 0.001 |
 Normal | 767 (26.8) | 663 (92.5) | 104 (14.5) | 0 (0.0) | 0 (0.0) |  |
 High | 2099 (73.2) | 54 (7.5) | 613 (85.5) | 716 (100.0) | 716 (100.0) |  |
Prior history of Diabetes | 810 (28.3) | 212 (29.6) | 181 (25.2) | 171 (23.9) | 246 (34.4) | < 0.001 |
Prior history of hypertension | 1477 (51.5) | 364 (50.8) | 338 (47.1) | 335 (46.8) | 440 (61.5) | < 0.001 |
Prior history of hyperlipidaemia | 868 (30.3) | 217 (30.3) | 187 (26.1) | 193 (27.0) | 271 (37.8) | < 0.001 |
Prior history of AMI | 138 (4.8) | 27 (3.8) | 30 (4.2) | 24 (3.4) | 57 (8.0) | < 0.001 |
Prior history of stroke | 150 (5.2) | 52 (7.3) | 28 (3.9) | 23 (3.2) | 47 (6.6) | 0.001 |
Prior history of renal disease | 60 (2.1) | 17 (2.4) | 7 (1.0) | 15 (2.1) | 21 (2.9) | 0.069 |