Table 1 Baseline characteristics comparisons according to CRP levels
Variables | Total (N = 420040) | Low (N = 273012) | High (N = 147028) | P Value |
|---|---|---|---|---|
Age | 56.5 ± 8.1 | 56.1 ± 8.1 | 57.5 ± 7.9 | < 0.0001 |
Female | 228,649 (54.4) | 144,038 (52.8) | 84,611 (57.5) | < 0.0001 |
White | 399,546 (95.1) | 260,022 (95.2) | 139,524 (94.9) | < 0.0001 |
Smoking | < 0.0001 | |||
Never | 230,775 (54.9) | 157,001 (57.5) | 73,774 (50.2) | |
Previous | 145,720 (34.7) | 92,232 (33.8) | 53,488 (36.4) | |
Current | 43,545 (10.4) | 23,779 (8.7) | 19,766 (13.4) | |
Drinking | < 0.0001 | |||
Never | 18,043 (4.3) | 10,281 (3.8) | 7762 (5.3) | |
Previous | 14,739 (3.5) | 8345 (3.1) | 6394 (4.3) | |
Current | 387,258 (92.2) | 254,386 (93.2) | 132,872 (90.4) | |
Body mass index | < 0.0001 | |||
<25 | 139,899 (33.3) | 114,151 (41.8) | 25,748 (17.5) | |
>=25 & <30 | 179,025 (42.6) | 118,695 (43.5) | 60,330 (41.0) | |
>=30 | 101,116 (24.1) | 40,166 (14.7) | 60,950 (41.5) | |
Income | < 0.0001 | |||
<18,000 | 81,141 (19.3) | 45,698 (16.7) | 35,443 (24.1) | |
18,000–30,999 | 91,979 (21.9) | 58,573 (21.5) | 33,406 (22.7) | |
31,000–51,999 | 94,443 (22.5) | 64,524 (23.6) | 29,919 (20.3) | |
52,000-100,000 | 73,991 (17.6) | 53,325 (19.5) | 20,666 (14.1) | |
>100,000 | 19,664 (4.7) | 15,046 (5.5) | 4618 (3.1) | |
Unknown | 58,822 (14.0) | 35,846 (13.1) | 22,976 (15.6) | |
Diabetes mellitus | < 0.0001 | |||
No | 395,322 (94.1) | 260,541 (95.4) | 134,781 (91.7) | |
Yes | 24,718 (5.9) | 12,471 (4.6) | 12,247 (8.3) | |
Dyslipidemia | < 0.0001 | |||
No | 217,461 (51.8) | 145,917 (53.4) | 71,544 (48.7) | |
Yes | 202,579 (48.2) | 127,095 (46.6) | 75,484 (51.3) | |
Hypertension | < 0.0001 | |||
No | 187,608 (44.7) | 135,067 (49.5) | 52,541 (35.7) | |
Yes | 232,432 (55.3) | 137,945 (50.5) | 94,487 (64.3) | |
Polygenic risk score | < 0.0001 | |||
Low | 139,876 (33.3) | 91,914 (33.7) | 47,962 (32.6) | |
Intermediate | 139,870 (33.3) | 90,626 (33.2) | 49,244 (33.5) | |
High | 140,294 (33.4) | 90,472 (33.1) | 49,822 (33.9) |