Table 1 Characteristics of the person-years accrued among cohort members based on biologic disease modifying anti-rheumatic drug (bDMARD) use status
Person-time as bDMARD naïve | Person-time of bDMARD exposure | |
|---|---|---|
Demographics | Person-years in 1000s (%) | |
Age (years) | ||
> 65 | 88.4 (64.1) | 27.8 (51.5) |
36–65 | 48.2 (34.9) | 25.2 (46.7) |
19–35 | 1.3 (0.9) | 1.0 (1.8) |
Sex | ||
Male | 123.8 (89.8) | 46.6 (86.3) |
Race | ||
White | 104.3 (75.7) | 43.2 (80) |
Black | 18.8 (13.7) | 6.4 (11.9) |
Other | 3.3 (2.4) | 1.4 (2.6) |
Missing | 11.4 (8.3) | 3 (5.5) |
Ethnicity | ||
Not Hispanic or Latino | 123.6 (89.7) | 49.4 (91.4) |
Hispanic or Latino | 5.8 (4.2) | 2.5 (4.6) |
Missing | 8.4 (6.1) | 2.2 (4) |
Smoking (baseline) | ||
No | 30 (21.8) | 10.8 (20) |
Yes | 53.7 (38.9) | 22.7 (41.9) |
BMI (baseline) | ||
≤18.5 | 1.0 (0.7) | 0.4 (0.8) |
18.5–25 | 26 (18.9) | 9.3 (17.2) |
25–30 | 46.2 (33.5) | 17.3 (32.1) |
>30 | 45.5 (33) | 19.7 (36.5) |
Missing | 19.2 (13.9) | 7.2 (13.4) |
Cohort Entry years | ||
2002–2007 | 69.7 (50) | 26.3 (51) |
2008–2013 | 49.2 (35) | 20 (38) |
2014–2019 | 21.3 (15) | 5.7 (11) |
RA characteristics (baseline) | ||
CRP (mg/L) | ||
0–3 | 14.5 (10.5) | 5.2 (9.6) |
3–30 | 44.9 (32.6) | 19.5 (36) |
30–50 | 5.5 (4) | 2.7 (5) |
50+ | 7.1 (5.2) | 3.7 (6.9) |
Missing | 65.9 (47.8) | 23 (42.5) |
Steroid use (prior year) | ||
No | 94.3 (68.4) | 36.4 (67.4) |
Yes | 43.6 (31.6) | 17.6 (32.6) |
RDCI | ||
0 | 26.3 (19) | 14.1 (26) |
1 | 34.4 (24.9) | 14.2 (26.3) |
2 | 37.1 (26.9) | 13.2 (24.4) |
3 | 21.7 (15.8) | 7.2 (13.3) |
4+ | 18.4 (13.4) | 5.4 (9.9) |