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Table 1 Prescriptions of disease-modifying anti-rheumatic drugs and steroids among patients with rheumatoid arthritis diagnosis by year

From: Exploring drug utilization patterns, healthcare resource utilization, and epidemiology of rheumatoid arthritis in Colombia: a retrospective claims database study

Medication

2017

2018

2019

2020

2021

n*

%**

n*

%**

n*

%**

n*

%**

n*

%**

csDMARDs

37,059

39.23

38,979

36.18

50,834

36.98

31,951

26.98

39,711

28.61

Chloroquine

12,298

13.02

12,425

11.53

14,122

10.27

8,309

7.02

11,451

8.25

Hydroxychloroquine

1,897

2.01

2,153

2.00

2,929

2.13

3,879

3.28

4,401

3.17

Leflunomide

16,846

17.83

18,710

17.37

23,629

17.19

15,450

13.05

17,224

12.41

Methotrexate

3,491

3.70

3,374

3.13

6,492

4.72

2,949

2.49

5,256

3.79

Sulfasalazine

2,527

2.67

2,317

2.15

3,662

2.66

1,364

1.15

1,379

0.99

bDMARDs

5,733

6.07

5,829

5.41

7,055

5.13

4,612

3.89

5,170

3.72

Abatacept

186

0.20

120

0.11

129

0.09

135

0.11

0

0.00

Adalimumab

1,031

1.09

929

0.86

1,593

1.16

517

0.44

1,080

0.78

Certolizumab pegol

217

0.23

86

0.08

162

0.12

181

0.15

126

0.09

Etanercept

2,147

2.27

2,332

2.16

2,381

1.73

1,651

1.39

1,582

1.14

Golimumab

59

0.06

38

0.04

48

0.03

70

0.06

46

0.03

Infliximab

138

0.15

127

0.12

163

0.12

132

0.11

163

0.12

Rituximab

923

0.98

1,127

1.05

1,450

1.05

1,117

0.94

1,243

0.90

Tocilizumab

1,032

1.09

1,070

0.99

1,129

0.82

809

0.68

930

0.67

tsDMARDs

859

0.91

1,163

1.08

1,579

1.15

1,925

1.63

2,488

1.79

Baricitinib

0

0.00

0

0.00

19

0.01

204

0.17

530

0.38

Tofacitinib

859

0.91

1,163

1.08

1,560

1.13

1,721

1.45

1,957

1.41

Upadacitinib

0

0.00

0

0.00

0

0.00

0

0.00

1

0.00

Glucocorticoids

54,474

57.66

25,394

23.57

63,201

45.97

33,898

28.62

67,774

48.83

Deflazacort

2,864

3.03

3,083

2.86

3,214

2.34

3,292

2.78

3,345

2.41

Dexamethasone

2,286

2.42

2,443

2.27

2,268

1.65

1,178

0.99

6,934

5.00

Hydrocortisone

450

0.48

534

0.50

565

0.41

297

0.25

190

0.14

Methylprednisolone

956

1.01

1,108

1.03

1,286

0.94

1,656

1.40

3,121

2.25

Prednisolone

47,918

50.72

18,226

16.92

55,868

40.64

27,475

23.20

54,184

39.04

Prednisone

2,846

3.01

961

0.89

714

0.52

395

0.33

343

0.25

  1. csDMARDs: conventional synthetic disease-modifying antirheumatic drugs; bDMARDs: biologic disease-modifying antirheumatic drugs; tsDMARDs: targeted synthetic disease-modifying antirheumatic drugs
  2. *Number of patients with prescriptions of each medication, **Proportion of patients with a prescription of each medicatio