The impact of anti-TNF-α therapy on leptin and inflammatory markers in rheumatoid arthritis patients: a case-control study

Table 1 Baseline demographic and laboratory characteristics of the participants

Variable	Healthy	Groups RA. Flare	RA. Remission	P value
Sex (Male/Female)	10/10	11/9	9/11	0.81
Age	35 ± 8.5	36 ± 7.43	38 ± 5.5	0.25
Height (cm)	163 ± 6.51	168 ± 5.65	164 ± 7.59	0.17
Weight (kg)	72.95 ± 10.83	72.05 ± 8.41	67.63 ± 14.03	0.29
BMI (kg/m²)	27.34 ± 3.57	25.79 ± 2.56	25.08 ± 3.94	0.11
Leptin (ng/ml)	7.59 ± 5.94	16.94 ± 7.72	14.49 ± 6.73	< 0.001
CRP (mg/l)	2.25 ± 2.4	38.95 ± 22.86	4.99 ± 2.21	< 0.001
ESR (mm/hr)	9.7 ± 2.65	43.35 ± 23.19	13.75 ± 3.41	< 0.001
RF	-	Positive:17 Negative: 3	Positive: 16 Negative:4	0.5
Anti-CCP	-	Positive:19 Negative: 1	Positive:18 Negative: 2	0.5

Data are presented as Mean ± SD, Categorical variables are compared by χ2 test. The rest of the variables are compared by ANOVA-test. BMI, body mass index, RF, rheumatoid factor; anti-CCP, anti-cyclic citrullinated peptides; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein

ISSN: 2520-1026