Table 1 Patient characteristics according to presence of gastrointestinal symptoms
SpA patients | Total | p-value | ||
|---|---|---|---|---|
≥2 GI symptoms | <2 GI symptoms | |||
n (%) | 64 (65.3) | 34 (34.6) | 98 (100.0) | |
Age (years)*** | 43 ± 11 | 41 ± 10 | 42 ± 10 | 0.455 |
Gender male | 35 (54.7) | 22 (64.7) | 57 (58.2) | 0.394 |
Male | ||||
Educational level (University) | ||||
University | 35 (54.7) | 11 (32.4) | 46 (46.9) | 0.163 |
Marital status (single) | ||||
Single | 14 (21.9) | 7 (20.6) | 23 (23.5) | 0.963 |
BMI > 25 kg/m2 | 40 (62.5) | 20 (58.8) | 60 (61.2) | 0.828 |
SpA subtype | ||||
axSpA | 51 (79.7) | 27 (79.4) | 78 (79.6) | 0.205 |
PsA | 5 (7.8) | 6 (17.6) | 11 (11.2) | |
ReA | 5 (7.8) | 0 (0) | 5 (5.1) | |
Undifferentiated SpA | 3 (4.7) | 1 (2.9) | 4 (4.1) | |
Axial involvement | 49 (76.6) | 27 (79.4) | 76 (77.6) | 0.805 |
Peripheral involvement | 15 (23.4) | 7 (20.6) | 22 (22.4) | 0.974 |
BASFI** | 5.3 (3.1–7.4) | 1.4 (0.2–5.3) | 4.1 (1.6–6.7) | <0.001* |
BASFI > 4 | 40 (62.5) | 13 (38.2) | 53 (54.1) | 0.033* |
BASDAI** | 5.6 (3.4–7.2) | 2.4 (0.8–5.7) | 4.9 (2.8–6.8) | <0.001* |
BASDAI > 4 | 43 (67.2) | 14 (41.4) | 57 (58.2) | 0.018* |
ASDAS CRP** | 2.8 (2.2–3.3) | 1.7 (1.1–2.7) | 2.5 (1.7–3.1) | <0.001* |
ASDAS CRP > 2.1 | 51 (79.7) | 14 (41.2) | 65 (66.3) | <0.001* |
ASDAS CRP > 3.5 | 11 (17.2) | 3 (8.8) | 14 (14.3) | 0.367 |
HLA*B27 (+) | 21 (32.8) | 11 (32.4) | 32 (32.7) | 0.963 |
CRP mg/dL** | 0.7 (0.2–2.3) | 0.8 (0.2–2.6) | 0.8 (0.2–2.6) | 0.988 |
CRP > 3 mg/dL | 9 (14.1) | 7 (20.6) | 16 (16.3) | 0.567 |
ESR mm/h** | 10 (5–20) | 10 (5–27) | 10 (5–21.5) | 0.973 |
ESR > 20 mm/h | 15 (23.4) | 11 (32.4) | 26 (26.5) | 0.471 |
Serum SIgA mg/mL** | 52 (46–66) | 52.1 (36–63) | 52.1 (42–65) | 0.183 |
Serum SIgA > 45 mg/mL | 52 (81.3) | 18 (52.9) | 70 (71.4) | 0.005* |
Calprotectin ng/mL** | 64 (43–153) | 49.3 (41–77) | 54.8 (43–130) | 0.129 |
Calprotectin > 120 ng/mL | 19 (29.7) | 5 (16.1) | 24 (25.3) | 0.21 |
Treatment | ||||
NSAID intake | 3 (4.7) | 3 (8.8) | 6 (6.1) | |
csDMARDs | 23 (35.9) | 10 (29.4) | 33 (33.7) | |
bDMARDs | 38 (59.4) | 21 (61.8) | 60 (60.2) | |
Mental health scales | ||||
PHQ-9 depression (n = 92)** | 10.5 (6–15.3) | 4 (2–12) | 8 (4–14) | 0.003* |
PSS-10 helplessness** | 11 (8–15) | 9 (3.5–14) | 10.5 (7–14) | 0.093 |
PSS-10 self-efficacy** | 5 (3–7.5) | 4 (1.8–8) | 5 (3–8) | 0.107 |