Fig. 2

Disease activity during pregnancy in women with rheumatoid arthritis (A) and spondyloarthritis (B, C). All “trimester x relapse” interactions, assessed by linear mixed models, are non-significant. The central mark is the median, the edges of the box are the 25th and 75th percentiles, the upper whisker is calculated as the maximum of (75th percentile + 1.5 × (75th percentile ─ 25th percentile)), and the lower whisker is calculated as the minimum of (25th percentile ─ 1.5 × (75th percentile ─ 25th percentile)). ASDAS-CRP: ankylosing spondylitis disease activity index using the C-reactive protein; BASDAI: bath ankylosing spondylitis disease activity index; DAS28-CRP: disease activity score in 28 joints using the C-reactive protein; T: trimester