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Table 1 Baseline characteristics of the patients with rheumatoid arthritis and spondyloarthritis

From: Disease activity during pregnancy in patients with rheumatoid arthritis or spondyloarthritis: results from the multicentre prospective GR2 study

 

RA (n = 53)

SpA (n = 71)

N

n (%)

or mean ± SD

or median [25th; 75th percentiles]

N

n (%)

or mean ± SD

or median [25th; 75th percentiles]

Age at conception, years

53

32.7 ± 5.0

71

31.7 ± 4.2

Disease duration, years

53

6 [3; 12]

70

5 [3; 9]

Current smoking

53

5 (9.4)

70

3/70 (4.3)

Current alcohol consumption

53

1 (1.9)

70

1/70 (1.4)

Body mass index, kg/m²

32

24.4 ± 5.8

41

24.9 ± 4.4

Nulliparity

52

30/52 (57.7)

71

34 (47.9)

Rheumatoid factor positive

51

39/51 (76.5)

ACPA positive

52

37/52 (71.2)

Erosion

52

24/52 (46.2)

HLA-B27 positive

71

40 (56.3)

SpA clinical manifestation

 Axial

70

36/70 (51.4)

 Peripheral

70

15/70 (21.4)

 Both

70

19/70 (27.1)

X-ray or MRI sacroiliitis

71

44 (62.0)

History of corticosteroid use

53

42 (79.2)

71

25 (35.2)

History of csDMARDs use

53

45 (84.9)

71

26 (36.6)

 Methotrexate

53

40 (75.5)

71

17 (23.9)

 Other

53

17 (32.1)

71

18 (25.4)

History of NSAIDs use

53

28 (52.8)

71

50 (70.4)

History of bDMARDs use

53

28 (52.8)

71

57 (80.3)

Disease flare in the 12 months prior to conception

43

15/43 (34.9)

36

35/36 (97.2)

Disease activity

 DAS28-CRP

40

2.6 ± 1.3

 DAS28-CRP-3

40

2.5 ± 1.1

 VAS global activity patient, /10

48

2 [1; 4]

56

2 [1; 6]

 VAS global activity practitioner, /10

40

1 [0; 3]

51

2 [0; 4]

 BASDAI

59

3.0 ± 2.1

 ASDAS-CRP

37

1.9 ± 1.2

 CRP, mg/L

42

3 [1; 10]

50

3 [1; 12]

 Tender joint count*

48

0 [0; 2]

62

0 [0; 0]

 Swollen joint count*

49

0 [0; 2]

62

0 [0; 0]

  1. Legend Data are presented as the number of patients (percentages), mean ± standard deviation, or median [25th; 75th percentiles]. *The number is calculated on 28 joints for patients with RA, and on 44 joints for patients with SpA. ACPA: anti-citrullinated peptide antibody; ASDAS-CRP: ankylosing spondylitis disease activity index using the C-reactive protein; BASDAI: bath ankylosing spondylitis disease activity index; bDMARDs: biologic disease modifying anti-rheumatic drugs; CRP: C-reactive protein; csDMARDS: conventional synthetic disease modifying anti-rheumatic drugs; DAS28-CRP: disease activity score in 28 joints using the C-reactive protein; DAS28-CRP-3: DAS28-CRP without the global assessment by the patient; HLA: human leucocyte antigen; MRI: magnetic resonance imaging; NSAIDs: non-steroidal anti-inflammatory drugs; RA: rheumatoid arthritis; SD standard deviation; SpA: spondyloarthritis; TNF: tumor necrosis factor; VAS: visual analogue scale