Table 1 Bivariate and multivariate analysis of factors associated with quality of life among SLE patients

Cognitive impairment^*

0.38

 Yes

80.35 (65.67–85.83)

-

0.750

 No

77.25 (65.42–88.48)

Depression^*

 Yes

63.22 (47.02–83.74)

-

0.003^****

-6.47

0.058

-13.17

0.23

 No

81.06 (71.11–87.20)

Anxiety^*

 Yes

65.33 (50.77–77.18)

-

< 0.001^****

-14.67

< 0.001^****

-20.49

-8.86

 No

84.20 (76.85–89.24)

Disease duration^**

-

0.24

0.011^****

0.03

0.165

-0.01

0.07

Age^**

-

0.18

0.058

0.14

0.288

-0.12

0.40

Disease activity^**

-

-0.15

0.117

-0.17

0.709

-1.08

0.74

Comorbidities^*

 Yes

81.51 (62.44–88)

0.680

 No

77.99 (65.67–86.75)

Steroid dose^**

-

-0.10

0.291

Immunosuppressants medications

Hydroxychloroquine^*

 Yes

80.86 (65.40–86.75)

-

0.790

 No

78.16 (69.56–87.76)

Mycophenolate sodium^*

 Yes

76.40 (54.52–85.49)

-

0.073

 No

81.49 (67.93–88.35)

Azathioprine^*

 Yes

78.16 (65.44–89.70)

-

0.573

 No

80 (65.53–86.77)

Methotrexate^*

 Yes

64.73 (51.56–86.28)

-

0.257

 No

80.18 (65.72–87.09)

Cyclosporine^*

 Yes

88.16 (73.50–89.24)

-

0.212

5.43

0.424

-7.97

18.82

 No

79.19 (65.41–86.62)

Organ Involvement

Musculoskeletal^*

 Yes

80.18 (65.61–87.13)

-

0.387

 No

73.70 (62.93–84.29)

Mucocutaneous^*

 Yes

79.75 (65.42–86.94)

-

0.519

 No

81.51 (68.98–92.31)

Renal^*

 Yes

81.34 (70.80–87.17)

-

0.431

 No

78.39 (65.06–86.87)

Hematology^*

 Yes

83.50 (65.22–88.79)

-

0.577

 No

78.58 (65.56–85.88)

Neuropsychiatric^*

 Yes

80 (50.49–88.28)

-

0.452

 No

79.75 (67.07–86.77)

Education level^*

 Primary

81.51 (59.05–91.16)

-

0.160

1.40

0.497

-2.68

5.48

 Secondary

77.48 (61.23–85.83)

 Tertiary

81.05 (66.83–89.02)