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Table 3 Characteristics of glucocorticoid-induced osteoporosis patients with/without major osteoporotic and hip fractures

From: Comparison of different intervention thresholds for the treatment of glucocorticoid-induced osteoporosis: a cross-sectional study

Variables

Major osteoporotic fracture (MOF)

Hip fracture (HF)

With fracture (n = 32)

Without fracture (n = 191)

Mean difference (95%CI)

p-value

With fracture (n = 2)

Without fracture (n = 221)

Mean difference (95%CI)

p-value

T-score at L1-4

-2.1 ± 1.44

-1.55 ± 1.16

-0.55 (-1.01, -0.09)

0.019

-2.9 ± 0.85

-1.62 ± 1.21

-1.28 (-2.97, 0.41)

0.137

T-score at total hip

-2.12 ± 1.13

-1.27 ± 0.95

-0.85 (-1.22, -0.48)

< 0.001

-4.35 ± 1.06

-1.36 ± 0.98

-2.99 (-4.37, -1.62)

< 0.001

T-score at FN

-2.63 ± 0.94

-1.81 ± 0.88

-0.82 (-1.16, -0.48)

< 0.001

-3.6 ± 1.41

-1.91 ± 0.92

-1.69 (-2.98, -0.41)

0.01

GC-FRAX with BMD, MOF (%)

25.17 ± 11.57

10.53 ± 6.68

14.64 (10.37, 18.91)

< 0.001

34.4 ± 26.02

12.41 ± 8.73

21.99 (-21.82, 25.48)

0.443

GC-FRAX with BMD, Hip (%)

12.43 ± 8.71

4.24 ± 4.49

8.19 (4.99, 11.39)

< 0.001

24.28 ± 21.74

5.23 ± 5.56

19.05 (-17.83, 21.39)

0.432

GC-FRAX without BMD, MOF (%)

20.61 ± 7.49

9.01 ± 5.61

11.6 (9.38, 13.82)

< 0.001

17.9 ± 7.21

10.59 ± 7.14

7.31 (-2.68, 17.3)

0.151

GC-FRAX without BMD, Hip (%)

10.07 ± 6.25

3.66 ± 3.79

6.41 (4.1, 8.72)

< 0.001

12.04 ± 9.85

4.5 ± 4.69

7.53 (0.92, 14.15)

0.026

  1. CI: Confidence interval. GC-FRAX: Glucocorticoid-adjusted FRAX. MOF: Major osteoporotic fracture. BMD: Bone mineral density