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Table 2 Baseline characteristics, laboratory findings and diagnoses of the 80 patients participating the follow-up

From: Do infections play a role in the development of chronic inflammatory arthritis? A 14–year follow-up study of patients with early arthritis

 

ReA

n = 31

UA

n = 16

RA

n = 15

Other *

n = 18

P-value

Age, years, mean

(range)

SD

30(9)

40(13)

40(12)

37(11)

0.010

Female, n (%)

16(52)

10(63)

13(87)

11(61)

0.19

Onset of joint symptoms, n (%)

acute

subacute

insidious

21(68)

8 (26)

2 (6)

9 (56)

2 (13)

5 (31)

2 (14)

4 (29)

8 (57)

10 (53)

5 (26)

4 (21)

0.005

Size of affected joints, n (%)

small

large

8 (27)

22 (73)

7 (44)

9 (56)

6 (43)

8 (57)

8 (42)

11 (58)

0.55

Type of arthritis, n (%)

monoarthritis

oligoarthritis

polyarthritis

3(10)

22 (76)

2 (7)

1 (6)

9 (64)

3 (21)

1(7)

2 (13)

10 (77)

2(12)

10 (59)

5 (29)

< 0.001

Back pain, n (%)

11(35)

4(25)

0(0)

2(11)

0.17

ESR mm/h, mean (SD)

53(33)

30(21)

47(28)

38(40)

0.11

RF positive, n (%)

1(3)

1(6)

5(33)

2(12)

< 0.001

HLA–B27 positive, n (%)

18(60)

4(27)

2(14)

4(22)

0.008

HLA–DR1 positive, n (%)

7(27)

4(29)

3(20)

6(40)

0.66

HLA–DR4 positive, n (%)

7(26)

5(36)

5(42)

1(6)

0.12

ASO positive, n (%)

4(13)

1(6)

2(14)

1(5)

0.77

Chlamydia antibodies positive, n (%)

10(32)

1(6)

2(14)

2(11)

0.13

Yersinia antibodies positive, n (%)

5(16)

0(0)

0(0)

0(0)

0.062

Salmonella antibodies positive, n (%)

2(7)

0(0)

0(0)

0(0)

0.66

Viral antibodies positive, n (%)

1(3)

1(6)

0(0)

3(22)

0.096

Any positivity of infection, n (%)

23(74)

6(38)

6(43)

7(39)

0.035

  1. Percentages were calculated for positive cases of the given samples. Samples were not available of all the patients
  2. ASO antistreptolysin O; RA rheumatoid arthritis; ReA reactive arthritis; UA undifferentiated arthritis
  3. * Sarcoid arthropathy 3, connective tissue disease 3, arthralgia 5, septic arthritis 1, rheumatic fever 2, arthrosis 2, rubella arthritis 1, and enteroarthritis associated with Crohn’s disease 1
  4. Anova chi (MonteCarlo)