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Table 1 Characteristics of the study participants

From: The C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index exhibits an L-shaped association with all-cause mortality in rheumatoid arthritis patients: a retrospective cohort study

Characteristics

Total

Alive

Deceased

p

N(%)

1101(100.0)

660(59.95)

441(40.05)

 

Sex, n(%)

   

0.008

 Male

466 (42.3)

258 (39.1)

208 (47.2)

 

 Female

635 (57.7)

402 (60.9)

233 (52.8)

 

Age, Mean ± SD

60.8 ± 14.3

54.9 ± 13.2

69.7 ± 10.9

< 0.001

Race, n (%)

   

< 0.001

 Mexican American

179 (16.3)

126 (19.1)

53 (12)

 

 Other Hispanic

72 (6.5)

56 (8.5)

16 (3.6)

 

 Non-Hispanic White

528 (48.0)

278 (42.1)

250 (56.7)

 

 Non-Hispanic Black

294 (26.7)

184 (27.9)

110 (24.9)

 

 Other Race - Including Multi-Racial

28 (2.5)

16 (2.4)

12 (2.7)

 

Education level, n(%)

   

< 0.001

 Less than 11th grade (Includes 12th grade with no diploma)

439 (39.9)

234 (35.5)

205 (46.5)

 

 High school graduate/GED or equivalent

264 (24.0)

142 (21.5)

122 (27.7)

 

 College or AA degree or above

398 (36.1)

284 (43)

114 (25.9)

 

Marital status, n(%)

   

< 0.001

 Married or Living with partner

477 (43.3)

259 (39.2)

218 (49.4)

 

 Other

624 (56.7)

401 (60.8)

223 (50.6)

 

Annual household income, n (%)

   

< 0.001

 ≤$24,999

521 (47.3)

272 (41.2)

249 (56.5)

 

 $25,000 to $64,999

391 (35.5)

236 (35.8)

155 (35.1)

 

 ≥$65,000

189 (17.2)

152 (23)

37 (8.4)

 

Hypertension, n(%)

   

< 0.001

 No

476 (43.2)

320 (48.5)

156 (35.4)

 

 Yes

625 (56.8)

340 (51.5)

285 (64.6)

 

Diabetes, n(%)

   

< 0.001

 No

871 (79.1)

545 (82.6)

326 (73.9)

 

 Yes

230 (20.9)

115 (17.4)

115 (26.1)

 

Chronic respiratory diseases, n (%)

   

0.471

 No

829 (75.3)

502 (76.1)

327 (74.1)

 

 Yes

272 (24.7)

158 (23.9)

114 (25.9)

 

Chronic heart disease, n (%)

   

< 0.001

 No

933 (84.7)

602 (91.2)

331 (75.1)

 

 Yes

168 (15.3)

58 (8.8)

110 (24.9)

 

Drug use, n (%)

   

< 0.001

 No

921 (83.7)

512 (77.6)

409 (92.7)

 

 Yes

180 (16.3)

148 (22.4)

32 (7.3)

 

Stroke, n (%)

   

< 0.001

 No

998 (90.6)

618 (93.6)

380 (86.2)

 

 Yes

103 (9.4)

42 (6.4)

61 (13.8)

 

Malignancy, n (%)

   

< 0.001

 No

940 (85.4)

586 (88.8)

354 (80.3)

 

 Yes

161 (14.6)

74 (11.2)

87 (19.7)

 

Smoking, n(%)

   

0.03

 No

440 (40.0)

281 (42.6)

159 (36.1)

 

 Yes

661 (60.0)

379 (57.4)

282 (63.9)

 

Alcohol uses, n(%)

   

0.018

 No

403 (36.6)

223 (33.8)

180 (40.8)

 

 Yes

698 (63.4)

437 (66.2)

261 (59.2)

 

BMI(kg/m2),Mean ± SD

30.3 ± 7.2

31.0 ± 7.4

29.4 ± 6.9

< 0.001

HGB(g/dL), Mean ± SD

13.9 ± 1.5

14.0 ± 1.5

13.8 ± 1.6

0.094

ALB(g/L), Mean ± SD

41.6 ± 3.4

41.8 ± 3.2

41.2 ± 3.7

0.012

GLB(g/L), Mean ± SD

31.1 ± 5.4

30.9 ± 5.1

31.4 ± 5.7

0.106

ALT(U/L), Median (IQR)

21.0 (16.0, 28.0)

21.0 (16.0, 28.0)

20.0 (15.0,28.0)

0.006

Scr(umol/L), Median (IQR)

74.3 (61.9, 90.2)

70.7 (61.9, 86.6)

79.6 (65.4,97.2)

< 0.001

CRP(mg/dL), Median (IQR)

0.3 (0.1, 0.8)

0.3 (0.1, 0.7)

0.4 (0.2, 0.8)

0.019

CALLY index(IQR)

41.1(17.2,104.4)

45.9(18.9,115.4)

28.6(12.4,66)

< 0.001

Log - CALLY

1.6 ± 0.6

1.7 ± 0.6

1.4 ± 0.6

< 0.001

Follow-up time(month)(IQR)

137.0(111.0,193.0)

152.0(130.0,210.0)

98.0(54.0,144.0)

< 0.001

  1. 1,101 RA participants were included in this study. Abbreviations used are as follows: BMI, body mass index; HGB, hemoglobin concentration; ALB, serum albumin concentration; GLB, serum globulin concentration; ALT, alanine aminotransferase concentration; Scr, serum creatinine concentration; CRP, C-reactive protein concentration; CALLY index, CRP-albumin-lymphocyte index